Senior Scientist – Discovery Protein Science – Amgen


If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

Senior Scientist – Discovery Protein Science

Open to candidates nationwide but work will be located in Burnaby, BC

What you will do

Let’s do this. Let’s change the world. In this vital role you will join the High Throughput Protein Solutions team in our Biologic Therapeutic Discovery organization. The team is responsible for the design and generation of key enabling DNA and protein reagents to support discovery of small and large molecule therapeutics and pioneering modalities.

As a successful candidate, you will supervise a high-performing team whose goal is to produce diverse protein reagents from mammalian expression systems to support the Amgen pipeline.  You will enable the strategic and scientific management of the group and will also actively participate in the science through hands-on lab work and implementation of high-throughput technologies. Alignment with our mammalian expression and purification teams in South San Francisco and collaborations with partner functions such as Biologics Discovery will be key.

Well-suited applicants will have a strong scientific background in recombinant protein expression and purification from mammalian systems and a deep scientific curiosity.  They will provide leadership and mentorship to the team and bring a positive approach to working in a collaborative research environment.

This role offers potential for advancement and career development. If you have a passion for science and want to be part of an organization discovering new medicines that will impact patients’ lives, we invite you to join us!

Basic Qualifications:

Ph.D. in Biochemistry, Cell Biology, Immunology, Molecular Biology, or a related discipline and 2 years of industry experience


Master’s Degree and 5 years of scientific experience

Bachelor’s degree and 7 years of scientific experience


Preferred Qualifications:

  • A track record of scientific accomplishments and project leadership in biologics drug development as evidenced by publications, patents, or pipeline contributions
  • 2+ years of leading an impactful team with a focus on mammalian cell lines, protein expression and purification
  • Deep technical expertise in recombinant protein expression in transient and stable mammalian hosts such as HEK293 and CHO
  • Broad knowledge of mammalian expression systems and willingness to explore new technologies
  • Expertise in purifying diverse protein types (e.g. extracellular domains, glycoproteins, monoclonal and multispecific antibodies, membrane proteins) using multiple chromatographic methods (e.g. affinity, ion exchange, size exclusion)
  • Experience with growing efficiency through automation is preferred
  • Strong written and verbal communication and interpersonal skills
  • Ability to encourage and grow a successful team, chart team goals into action, and forge collaborations with partner functions



What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

  • Vast opportunities to learn and move up and across our global organization
  • Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
  • Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits


Apply now

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.
If interested, please apply to R-142080 on